In life sciences, confocal fluorescence microscopy (CFM) is widely regarded for producing high-resolution cellular images. However, it requires fluorescent staining, which poses risks of ...

Confocal microscopy is a specialized fluorescence imaging technique that scientists use to acquire images at greater resolution than conventional microscopy. 1 In addition to scanning the lateral x ...

Biologists are very interested in how proteins, lipids and other compounds are organized and interact in systems. Very few organizational details can be gained by using standard transmission-based ...

Peking University, May 23, 2025: A collaboration between team led by Xi Peng, researcher from PKU College of Future Technology, and Qu Junle from Shenzhen University developed an innovative approach ...

A protein's function depends on its movement inside a cell and interactions with other proteins and biological structures. Biologists who want to watch proteins working in living cells frequently turn ...

A team at South Korea's Pohang University of Science and Technology (POSTECH) has developed a way to process low-resolution label-free photoacoustic images into high-resolution virtually stained ...

Computational fluorescence microscopy (CFM) requires accurate point spread function (PSF) characterization for high-quality imaging. We propose a sample prior–based PSF decoupling method, where ...

In a recent article published in Nature Communications, researchers introduced NanoPlex, a novel strategy designed to overcome limitations in fluorescence microscopy by utilizing engineered secondary ...

Researchers have built a tiny, lightweight microscope that captures neuron activity with unprecedented speed that can be used in freely moving animals. The new tool could give scientists a more ...