NUDT5 enzyme acts as a molecular scaffold that maintains metabolic balance. Inside every cell, a finely tuned metabolic network determines when to build, recycle or stop producing essential molecules.

Dihydropteroate synthase (DHPS) is a crucial enzyme in the folate biosynthetic pathway, catalysing the formation of essential folate cofactors that underpin DNA synthesis and cellular functioning.

Inside every cell, a finely tuned metabolic network determines when to build, recycle, or stop producing essential molecules. A central part of this network is folate metabolism, a process that ...

Although they number from 1 (thiamine) to 12 (cobalamin), there are eight B vitamins—don't bother seeking numbers 4, 8, 10, or 11. The rest are all facilitators of the nervous system and tend to work ...

This review synthesizes current knowledge on the intricate metabolic interplay between folate and biopterin cofactors, emphasizing their structural similarities, shared enzymatic pathways, and ...

It is well established that folic acid supplementation can significantly reduce the risk of birth defects, including neural tube defects like spina bifida, the most common birth defect of the central ...

A new review reveals how folic acid can act as both a friend and foe in breast cancer, protecting at moderate doses, but potentially fueling tumor growth when intake is excessive or genes go awry.