Osteogenesis imperfecta (OI) refers to a group of rare genetic bone disorders that results in the formation of fragile bones. In patients with OI, the matrix that makes up the bone has been found to ...

Spinal deformities such as scoliosis and kyphosis are among the most serious complications of neurofibromatosis type 1 (NF1), a genetic disorder that affects about one in 3,000 people.

Researchers identify bone-forming cells as the driver of scoliosis caused by a genetic disorder, which can be prevented ...

Using CRISPR-based technologies, the MoDeL team introduces precise genetic modifications in mice, enabling researchers to uncover how mammalian genes maintain health and contribute to disease.

GemPharmatech, a global leader in preclinical research solutions and genetically-engineered mouse models, today announced a collaboration with Memorial Sloan Kettering Cancer Center (MSK) to ...

Immune checkpoint therapy (ICT) is a front-line treatment for lung cancer; however, low mutational burden and ‘non-T cell inflamed’ signatures predict poor responses to ICT in ~50% of patients.

Pictured are two of Colossal's "woolly mice". Dallas-based biotech startup Colossal aims to bring the woolly mammoth back from extinction through genetic engineering. As part of that process, the ...