The structures of the Fc regions of human IgG, IgE and IgA have been solved, revealing similarities in overall domain arrangements. The extracellular domains of the human IgG Fc receptors FcγRIIa, ...

The immune system’s capacity to distinguish self from non-self is in large part mediated by immunoglobulins, with IgG playing a pivotal role in both protective and pathological responses.

Aggregation reduces the active ingredient content in the sample, resulting in a reduction in efficacy Aggregation triggers immunogenic responses in the body. Triggering of immunogenic responses ...

Science, founded by Thomas A. Edison in 1880 and published by AAAS, today ranks as the world's largest circulation general science journal. Published 51 times a year, Science is renowned for its ...

Vertebrates with a defined immune system, such as humans, have an immune response consisting of an innate and adaptive response, also known as a specific response. The specific response is tailored to ...