The mechanism of skeletal muscle contraction is a process that relies on calcium signaling. However, the physiological role of calcium-induced calcium release (CICR) through the ryanodine receptor ...

In a recent study in Nature Neuroscience, researchers investigated whether the R136S genetic mutation protected against apolipoprotein E4 (APOE4)-induced late-onset Alzheimer’s disease (LOAD). Study: ...

What if doctors could look at a person’s DNA and not only spot a harmful mutation, but also predict the kind of disease it may cause—before symptoms fully appear? Scientists at the Icahn School of ...

Researchers working on an incurable blood cancer can now use a new lab model that could make testing potential new treatments and diagnostics easier and quicker, new research has found. Working with ...

A recently published study in Nature Communications, led by a group from the Bellvitge Biomedical Research Institute (IDIBELL) with the participation of the Germans Trias i Pujol Research Institute ...

Forward genetic studies use meiotic mapping to adduce evidence that a particular mutation, normally induced by a germline mutagen, is causative of a particular phenotype. Particularly in small ...