Several challenges may be presented when processing powder blends: the blend may be prone to segregation, the creation of agglomerates may influence homogeneity, or component powders may poorly flow ...

Using a novel automated microfilling system, the authors demonstrate that roller compaction followed by milling is a viable preprocessing technique for high-dose chemical-in-capsule dosage forms. The ...

Granulation and compression are two very important processes that are carried out extensively by most pharmaceutical companies. However, the theory of granulation is little understood and the ...

To illustrate the intelligent-compaction (IC) roller’s potential to increase production, Kevin Garcia—road and paving construction segment manager for Trimble Navigation—relates an experiment Trimble ...

There are significant benefits to dry granulation, in terms of cost-reduction and processing, and it can be used with sensitive materials. However, there is little indication as to which process ...