Abstract Hyaline cartilage’s inability to self-repair can lead to osteoarthritis and joint replacement. Various treatments, including cell therapy, have been developed for cartilage damage. …

Jan 6, 2024 · Full-thickness knee cartilage defects are a potential source of significant morbidity for patients and incur an increased risk for early degenerative joint disease. Recent decades …

Feb 11, 2025 · Purpose of Review Cartilage injury does not heal spontaneously. The current cell-based cartilage treatments have either demonstrated poor clinical outcomes, require two …

Aug 6, 2021 · Regenerative medicine, using cells as therapeutic agents for the repair or regeneration of tissues and organs, offers great hope for the future of medicine. Cell therapy …

The current gold standard treatment for OA is total joint arthroplasty, but this is also not suitable to all patients. 3, 13 In this review, we will discuss the current cell therapies for cartilage defects …

Aug 7, 2025 · Focal chondral defects of the knee are a common cause of pain and functional limitation in active individuals and may predispose to early degenerative joint changes. Given …

Dec 8, 2025 · Osteoarthritis (OA) is a progressive joint disease characterized by cartilage degeneration. Although the current use of mesenchymal stromal cells (MSCs) treatment …

While these will target small cartilage lesions and will possibly lead to the long-awaited disease-modifying OA drugs (DMOADs), more comprehensive approaches relying on exogenous cells …

5 days ago · OA is a complex, degenerative and incurable disease, involving multiple joint tissues and pain mechanisms. Scarcell’s patented aGF Therapy is uniquely designed to address all …

Mar 31, 2023 · Resulting repair of cartilage defects, such as osteoarthritis (OA), is highly challenging in clinical treatment. Fortunately, the development of tissue engineering provides a …