Integrin beta 2 - Wikipedia
Genetically-inherited deficiencies in the ITGB2 gene can lead to reduced surface expression of the CD18 protein, leading to the immunodeficiency leukocyte adhesion deficiency.
CD18 - an overview | ScienceDirect Topics
CD18 is a 95 kDa glycoprotein that is a subunit of LFA-1. It consists of extracellular, transmembrane, and cytoplasmic domains, with potential glycosylation sites and cysteines for …
What Is CD18 and Its Role in the Immune System? - Biology ...
Jul 27, 2025 · CD18 is a protein found on the surface of various immune cells, particularly white blood cells (leukocytes). This protein plays an important role in the body’s defense system, …
Frontiers | β2 Integrin CD11d/CD18: From Expression to an ...
CD11d/CD18 is the most recently discovered and least understood beta 2 integrin. Known CD11d adhesive mechanisms contribute to both extravasation and mesench...
The downregulated membrane expression of CD18 in CD34+ cells ...
CD18 is the common beta subunit of β2 integrins, which are expressed on hematopoietic cells. β2 integrins are essential for cell adhesion and leukocyte trafficking. Here we have analyzed the …
CD18 – Knowledge and References – Taylor & Francis
CD18 is a subunit of the β2 integrin family and a leukocyte adhesion molecule that plays a crucial role in immune function. It is unique among integrins for its structure and function and is …
What are CD18 inhibitors and how do they work? - Patsnap
Jun 21, 2024 · CD18, also known as integrin β2, is a protein that forms part of several integrins, including LFA-1, Mac-1, and p150,95. These integrins are pivotal for leukocyte adhesion and …